約 5,147,519 件
https://w.atwiki.jp/minecraftinbackrooms/pages/106.html
Level !-! サブタイトル Hotel Chase（ホテルチェイス） 概要 Level !-!はLevel !のサブレベルであり、赤く警報音が鳴り響くホテルの廊下のような空間です。 Level !と同じように後ろから大量のエンティティが迫ってくるのでその大群に追いつかれないよう逃げながら出口を探しましょう。 途中青い扉があり、その先には青い廊下と呼ばれる安全地帯があります。青い廊下にはエンティティは入ってこれないようです。 青い廊下 青い廊下はこのレベルで見られる安全地帯です。 廊下を走っていると稀に青い扉を見つけることが出来ます。 その中に入るとこの青い廊下にたどり着きます。 ここにはエンティティは、入ってくることが出来ないためゆっくりとくつろぐことが出来ます。 施設 共有チェスト 青い廊下にあります。 Entities ゾンビ まれに、通常より年齢が低いと見られるゾンビが出現することがあります。 通常個体よりかなり素早いため、一刻も早く逃げ出すことが賢明です。 入口 Level 2でノークリップをすると50%の確率でLevel !-!に到達します。 Level !で左にある開いたドアに入るとLevel !-!に到達します。 出口 階段を上がるとPromised Landに到達します。 開いたドアに入るとlevel !に到達します。
https://w.atwiki.jp/todo314/pages/238.html
Control Profiles of Complex Networks Justin Ruths, Derek Ruths Science 2014 概要 Network Controllabilityには次数分布が大事 特に重要なのはsourceとsinkの数 Network Controllability 微分方程式 dx(t)/dt = Ax(t)+Bu(t) A 隣接行列，B 入力行列 例 脳，人の意見，空港の利用客数 uをうまく設定してxを任意の状態にしたい 実際には… 辺の重みが分からん（ ＾ω＾）おっ Structural Controllability 辺の重みを（ゼロ以外に）定めてcontrollableにできる Science 2014-06-30 19 20 57 (Mon)
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HTML5基本構造 HTML5の基礎組み立て DOCTYPE 宣言（DOCTYPE スイッチ） HTML5基本構造 参考サイト：http //www.htmq.com/html5/002.shtml より明確に文書構造を示すことができる フォームの入力補助やチェック機能を属性で指定できる 動画や音声データをHTMLからシンプルに扱える APIの追加により、ウェブアプリケーションが構築しやすくなる HTML5で追加される予定の要素（タグ） HTML5で廃止される予定の要素（タグ） HTML5の基礎組み立て !DOCTYPE html html lang="ja" head title TAG Design /title !-- 文字コード -- meta http-equiv="Content-Type" content="text/html; charset=utf-8" !-- 検索キーワード -- meta name="keywords" content="keyword1,keyword2" !-- サイト説明文 -- meta name="description" content="This is test page !" !-- 作者情報 -- meta name="author" content="miyoshi" !-- 著作権情報 -- meta name="copyright" content="miyoshi" !-- css外部参照 -- link rel="stylesheet" type="text/css" href="../css/style.css" !-- google api - jquery -- script type="text/javascript" src="https //ajax.googleapis.com/ajax/libs/jquery/1.7.2/jquery.min.js" /script /head body div id="wrapper" header h1 TAG Design /h1 h2 ~ tag design ~ /h2 /header div id="main" ul li class="about" a href="#" About Us /a /li /ul /div footer li a href="#" 個人情報の取り扱いについて /a /li li a href="#" サイトマップ /a /li p Copyright copy; 2012 TAG Design /p /footer /div /body /html DOCTYPE 宣言（DOCTYPE スイッチ） 参考サイト：http //2xup.org/log/2007/07/27-2111 各ブラウザの DOCTYPE スイッチ対応表：http //spreadsheets.google.com/pub?key=pbrvd2wQKc03fJ5QWgYr-Cw gid=3 HTML5はDTDがいらない：http //withd.jp/web/tips/standard/3947.html?page=2 DTDwiki：http //ja.wikipedia.org/wiki/Document_Type_Definition オンの状態 standards mode (標準準拠モード) 仕様に準拠した厳格な表示モード オフの状態 quirks mode (後方 (過去) 互換モード) 仕様に準拠していない古いブラウザとの互換 css3フォーマット @import url(http //fonts.googleapis.com/css?family=Fredericka+the+Great); body, header, nav, article, aside, footer, div, ul, li, h1, h2, p { margin 0; padding 0; } body { text-align center; line-height 1.5; min-width 800px; background-color #f5f5f1; color #666666; font-family Fredericka the Great , cursive; font-size 62.5%; }
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!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http //www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd" html xmlns="http //www.w3.org/1999/xhtml" lang="ja" xml lang="ja" head meta http-equiv="Content-Type" content="text/html; charset=utf-8" / meta http-equiv="Content-Style-Type" content="text/css; charset=UTF-8" / meta http-equiv="content-script-type" content="text/javascript" / title tesssttttttttttttttttt - トップページ /title link rel="start" href="/gokuu/" / link rel="stylesheet" type="text/css" href="http //www39.atwiki.jp/_skin/base_021mandarin.css" media="all" / link rel="alternate" href="/gokuu/rss10.xml" type="application/rss+xml" title="RSS" / style type="text/css" media="screen" !-- body,html { margin 0 !important; padding 0 !important; } .box { zoom 100%; } .box after { clear both; content "."; display block; height 0; visibility hidden; } .hidden { display none; } .disableLink { color #777 !important; cursor default !important; display block !important; 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https://w.atwiki.jp/metalmetabo/pages/33.html
- visitors Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner-Doudoroff pathway nih.gov [HTML]I Borodina, C Scholler, A Eliasson, J … - Applied and …, 2005 - Am Soc Microbiol http //scholar.google.com/scholar?q=related vbWz9Ak9HjwJ scholar.google.com/ hl=ja as_sdt=2000 Streptomyces tenebrarius is an industrially important microorganism, producing an antibiotic complex that mainly consists of the aminoglycosides apramycin, tobramycin carbamate, and kanamycin B carbamate. When S. tenebrarius is used for industrial tobramycin ... Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network J Lee, H Yun, AM Feist, BØ Palsson, SY Lee - Applied microbiology and …, 2008 - Springer http //scholar.google.com/scholar?q=related 6k93cgR0CzwJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. GENOMICS AND PROTEOMICS Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network Joungmin Lee Hongseok Yun Adam M. Feist Bernhard Ø. Palsson Sang Yup Lee ... Metabolic networks in motion 13C-based flux analysis nih.gov [HTML]U Sauer - Molecular systems biology, 2006 - nature.com http //scholar.google.com/scholar?q=related B0vTesydGZwJ scholar.google.com/ hl=ja as_sdt=2000 ... Curr Opin Biotechnol 16 350–355 | Article | PubMed | ISI | ChemPort |; Borodina I, Schöller C, Eliasson A, Nielsen J (2005) Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner–Doudoroff pathway. ... Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks hindawi.com [PDF]O Fiehn - Comparative and Functional Genomics, 2001 - Wiley Online Library http //scholar.google.com/scholar?q=related -r0O-RbpfxsJ scholar.google.com/ hl=ja as_sdt=2000 ... Metabolomics. The obvious next step in metabolic network analysis is to try to determine metabolic snapshots in a broad and comprehensive way. ... 13 Christensen B, Nielsen J. Metabolic network analysis a powerful tool in metabolic engineering. ... A metabolic network analysis NMR experiment design tool with user interface-driven model construction for depth-first search analysis T Zhu, C Phalakornkule, S Ghosh, IE Grossmann, … - Metabolic …, 2003 - Elsevier http //scholar.google.com/scholar?q=related Ov3p-3IVXxsJ scholar.google.com/ hl=ja as_sdt=2000 A Windows program for metabolic engineering analysis and experimental design has been developed. A graphical user interface enables the pictorial, “on-screen” construction of a metabolic network. Once a model is composed, balance equations are automatically generated. ... Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology plos.org [HTML]J Puchałka, MA Oberhardt, M Godinho, A Bielecka, … - PLoS Comput …, 2008 - dx.plos.org PLoS Computational Biology is an open-access. http //scholar.google.com/scholar?q=related V6wktboEeLMJ scholar.google.com/ hl=ja as_sdt=2000 Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae cshlp.org [HTML]MJ Herrgård, BS Lee, V Portnoy, BØ … - Genome research, 2006 - genome.cshlp.org http //scholar.google.com/scholar?q=related -IQUN4gFKUgJ scholar.google.com/ hl=ja as_sdt=2000 ... biomass composition). The integration of the metabolic network analysis and the transcriptional regulatory network model described above is accomplished using the regulated flux balance analysis approach (Covert et al. 2001). In ... Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies ulaval.ca [PDF]PA Vanrolleghem, P de Jong-Gubbels, … - Biotechnology …, 1996 - interscience.wiley.com http //scholar.google.com/scholar?q=related jaCs_pUlSXcJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. ARTICLES Validation of a Metabolic Network for Saccharomyces cerevisiae Using Mixed Substrate Studies Peter A. Vanrolleghem,*,† Patricia de Jong-Gubbels,‡ Walter M. van Gulik,§ Jack T. Pronk,‡ Johannes P. van Dijken,‡ and Sef Heijnen† ... Metabolic‐flux analysis of Saccharomyces cerevisiae CEN. PK113‐7D based on mass isotopomer measurements of 13C‐labeled primary metabolites WA Winden, JC Dam, C Ras, RJ Kleijn, JL … - FEMS yeast …, 2005 - Wiley Online Library Skip to Main Content. ... http //scholar.google.com/scholar?q=related fM6Xi9-F_GIJ scholar.google.com/ hl=ja as_sdt=2000 The efficiency of multi-target drugs the network approach might help drug design arxiv.org [PDF]P Csermely, V Agoston, S Pongor - Trends in pharmacological sciences, 2005 - Elsevier http //scholar.google.com/scholar?q=related U0rlpj3tgrYJ scholar.google.com/ hl=ja as_sdt=2000 ... 6111–6121. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (53). 8 B. Papp et al., Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast, Nature 429 (2004), pp. 661–664. Full Text via CrossRef | View Record in Scopus |.
https://w.atwiki.jp/metalmetabo/pages/34.html
- visitors In vivo analysis of intracellular amino acid labelings by GC/MS. C Wittmann, M Hans, E Heinzle - Analytical biochemistry, 2002 - mendeley.com ... TBDMS derivatization of amino acids is especially useful in metabolic network analysis, because M-57 fragments containing the entire carbon skeleton of the analyte can be observed by GC/MS with high signal intensities 8. The potential of the method is exemplified for ... Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose nih.gov [HTML]P Kiefer, E Heinzle, O Zelder, C … - Applied and …, 2004 - Am Soc Microbiol ... A comprehensive approach to 13 C tracer studies, labeling measurements by gas chromatography-mass spectrometry, metabolite balancing, and isotopomer modeling, was applied for comparative metabolic network analysis of lysine-producing Corynebacterium glutamicum ... It is all about metabolic fluxes nih.gov [HTML]J Nielsen - Journal of bacteriology, 2003 - Am Soc Microbiol http //scholar.google.com/scholar?q=related xAvLLrdbbNYJ scholar.google.com/ hl=ja as_sdt=2000 ... I. Experimental observations. Biotechnol. Bioeng. 55 305-316.[CrossRef] 21; Thykaer, J., B. Christensen, and J. Nielsen. 2002. Metabolic network analysis of an adipoyl-7-ADCA producing strain of Penicillium chrysogenum elucidation of adipate degradation.Metab. Eng. ... Using topology of the metabolic network to predict viability of mutant strains biomedcentral.com [PDF]Z Wunderlich, L Mirny - Genome Biology, 2005 - biomedcentral.com http //scholar.google.com/scholar?q=related sTavonuje7wJ scholar.google.com/ hl=ja as_sdt=2000 ... Ph.D. Thesis. University of Leeds; 1994. 14. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 2004, 429(6992) 661-664. 15. Jeong H, Tombor B, Albert R, Oltvai ZN, Barabasi AL The large-scale ... Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell … plantphysiol.org [HTML]H Eubel, EH Meyer, NL Taylor, JD Bussell, N O … - Plant …, 2008 - Am Soc Plant Biol http //scholar.google.com/scholar?q=related aCgbR-dAtyMJ scholar.google.com/ hl=ja as_sdt=2000 ... This is aided by a metabolic network analysis that reveals a tight integration of functions and highlights specific metabolite nodes that most probably represent entry and exit metabolites that could require transport across the peroxisomal membrane. ... High-throughput phenomics experimental methods for mapping fluxomes bjmu.cn [PDF]U Sauer - Current opinion in Biotechnology, 2004 - Elsevier http //scholar.google.com/scholar?q=related XvhSxXXwbn4J scholar.google.com/ hl=ja as_sdt=2000 ... From its early days when material fluxes were balanced within assumed reaction networks [7.], metabolic network analysis [6. and 8.] has matured to actually identify the topology of active reactions and pathways and to quantify the molecular flux through them on a variety of ... Use of genome-scale microbial models for metabolic engineering KR Patil, M Åkesson, J Nielsen - Current opinion in biotechnology, 2004 - Elsevier http //scholar.google.com/scholar?q=related oAOz5SBTVHAJ scholar.google.com/ hl=ja as_sdt=2000 ... incorporate genome-scale biological data. Genome-scale stoichiometric models of microorganisms represent a first step in this direction. FBA, flux balance analysis; MFA, metabolic flux analysis; MNA, metabolic network analysis. ... Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression nih.gov [HTML]AK Gombert, M Moreira dos Santos, B … - Journal of …, 2001 - Am Soc Microbiol http //scholar.google.com/scholar?q=related R5V_AodxCrwJ scholar.google.com/ hl=ja as_sdt=2000 ... flux estimates. The use of 13 C-labeled substrates enables both identification of the metabolic network structure and quantification of the metabolic fluxes and is therefore referred to as metabolic network analysis (5). This kind ... Metabolic flux analysis of Escherichia coli K12 grown on 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method freelogy.org [PDF]J Zhao, K Shimizu - Journal of biotechnology, 2003 - Elsevier http //scholar.google.com/scholar?q=related w1m-5IKYKpsJ scholar.google.com/ hl=ja as_sdt=2000 Structural and functional analysis of cellular networks with CellNetAnalyzer biomedcentral.com [HTML]S Klamt, J Saez-Rodriguez, ED Gilles - BMC Systems Biology, 2007 - biomedcentral.com http //scholar.google.com/scholar?q=related bzwlVku0FL8J scholar.google.com/ hl=ja as_sdt=2000 ... CNA extends its predecessor FluxAnalyzer, originally developed for metabolic network analysis[7], by new methods for signalling and regulatory networks, ie for networks where signal flows are dominating (in contrast to mass flows in metabolic networks). ...
https://w.atwiki.jp/metalmetabo/pages/29.html
- visitors Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N 315 an initial draft to the two-dimensional annotation biomedcentral.com [HTML]SA Becker, BØ Palsson - BMC microbiology, 2005 - biomedcentral.com http //scholar.google.com/scholar?q=related 829ZIciJNnkJ scholar.google.com/ hl=ja as_sdt=2000 ... J Biol Chem 2004, 279 39532-39540. PubMed Abstract | Publisher Full Text OpenURL. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 2004, 429 661-664. ... Adaptive evolution of bacterial metabolic networks by horizontal gene transfer linkgroup.hu [PDF]C Pál, B Papp, MJ Lercher - Nature Genetics, 2005 - nature.com http //scholar.google.com/scholar?q=related j65eRY_pFyIJ scholar.google.com/ hl=ja as_sdt=2000 ... were present. Gene families with more than one member in E. coli K-12 were excluded from the analysis. Metabolic network analysis. We examined the reconstructed metabolic network (iJR904 GSM/GPR) of E. coli K-12. We ... Network analysis of metabolic enzyme evolution in Escherichia coli biomedcentral.com [HTML]S Light, P Kraulis - BMC bioinformatics, 2004 - biomedcentral.com http //scholar.google.com/scholar?q=related M0gfPqO-WsQJ scholar.google.com/ hl=ja as_sdt=2000 ... representation of metabolic pathways where the substrates and products are the vertices and the enzymes catalyzing the reactions are the edges (Figure 1). The type of network representation used in our study has been used before for metabolic network analysis where it has ... Metabolic network analysis on Phaffia rhodozyma yeast using 13C-labeled glucose and gas chromatography-mass spectrometry C Cannizzaro, B Christensen, J Nielsen, U … - Metabolic Engineering, 2004 - Elsevier http //scholar.google.com/scholar?q=related xVq5KkaMAd4J scholar.google.com/ hl=ja as_sdt=2000 Amino acid labeling patterns, as determined by GC–MS, were in accordance with a metabolic network consisting of the Embden–Meyerhof–Parnas pathway, the pentose phosphate pathway, and the TCA cycle. Glucose was mainly consumed along the pentose ... Metabolic network analysis integrated with transcript verification for sequenced genomes A Manichaikul, L Ghamsari, EFY Hom, C Lin, RR … - Nature methods, 2009 - nature.com http //scholar.google.com/scholar?q=related qlItzvkCLowJ scholar.google.com/ hl=ja as_sdt=2000 Present availability of genome sequences for diverse microorganisms brings opportunities for metabolic engineering through systems-level characterization of these organisms metabolic networks 1 . Such efforts require both functional and structural annotation of metabolic ... High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints E Fischer, N Zamboni, U Sauer - Analytical biochemistry, 2004 - Elsevier http //scholar.google.com/scholar?q=related AGqwTbFzQbYJ scholar.google.com/ hl=ja as_sdt=2000 Influence of metabolic network structure and function on enzyme evolution biomedcentral.com [HTML]D Vitkup, P Kharchenko, A Wagner - Genome biology, 2006 - biomedcentral.com http //scholar.google.com/scholar?q=related tyk--z8xdr0J scholar.google.com/ hl=ja as_sdt=2000 ... Cold Spring Harbor Press, NY; 1982. OpenURL. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of the enzyme dispensability in yeast. Nature 2004,429 661-664. PubMed Abstract | Publisher Full Text OpenURL. ... Metabolomics-and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii genetics.org [HTML]P May, S Wienkoop, S Kempa, B Usadel, N … - Genetics, 2008 - Genetics Soc America http //scholar.google.com/scholar?q=related lrqK6GwpxFIJ scholar.google.com/ hl=ja as_sdt=2000 ... Furthermore, the results will contribute to an improvement of metabolic databases. Presently, our methods are limited to one selected large-scale metabolic network analysis technique, the method of network expansion. Further ... Metabolic network analysis during fed-batch cultivation of Corynebacterium glutamicum for pantothenic acid production first quantitative data and analysis of by- … C Chassagnole, A Diano, F Létisse, ND Lindley - Journal of biotechnology, 2003 - Elsevier http //scholar.google.com/scholar?q=related CJC7H27nMvMJ scholar.google.com/ hl=ja as_sdt=2000 A first generation genetically modified strain of Corynebacterium glutamicum has been assessed for its potential to synthesise and accumulate the vitamin pantothenic acid in the medium using fed-batch cultivation technology, with biomass concentration controlled by isoleucine ... Metabolic modeling of microbial strains in silico ru.nl [PDF]MW Covert, CH Schilling, I Famili, JS Edwards, … - Trends in Biochemical …, 2001 - Elsevier http //scholar.google.com/scholar?q=related pjh6sWp3MRMJ scholar.google.com/ hl=ja as_sdt=2000 ... labeling experiments. Adv. Biochem. Eng. Biotechnol. 54, pp. 109–154. Christensen, B. and Nielsen, J., Metabolic network analysis. A powerful tool in metabolic engineering. Adv. Biochem. Eng. Biotechnol. 66, pp. 209–231. The ...
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On Compressing Social Networks Flavio Chierichetti, Ravi Kumar, Silvio Lattanzi, Michael Mitzenmacher, Alessandro Panconesi, Prabhakar Raghavan KDD 2009 概要 ウェブグラフの圧縮は既にある 平均3bits ソーシャルネットワークの場合は？ 問題を定式化、NP-hardだけど適当にヒューリスティクスで頑張る ウェブグラフの圧縮 [Boldi-Vigna. WWW 04] The WebGraph Framework I Compression Techniquesとか URL順の恩恵がある 類似性と局所性 ノード順が大事 Compression-friendly ordering 問題定式化 MLogA $$ \sum_{(u,v) \in E}\lg|\pi(u)-\pi(v)| $$ MLogGapA $$ \sum_{u \in V}f_\pi(u, N^+(u)) $$ $$ f_\pi(u, N^+(u)) = \sum_{i}\lg|\pi(u_i)-\pi(u_{i-1})| $$ 隣接リスト表現を考えて隣り合う点対のコストを考える 両方夜もNP-hard expander-likeだと圧縮しにくい ヒューリスティクス 出近傍のMinHashでソート（Jaccard係数が大きければ近くにする） Preferential attachmentで正当化つき 実験 色々やりました まとめ 良い論文 KDD グラフ圧縮 2017/06/11
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