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【登録タグ CD CDP いーえるPCD 全国配信】 前作 今作 次作 一度きりの物語 交差する想像共感 SIDE-RPOINT OF THE GLANCE - Another Ver 狂騒世界のファンタジア いーえるP 流通：配信 発売：2011年12月21日 価格：￥150 レーベル：KARENT ジャケットイラスト：ももぱん iTunes Storeで購入 CD紹介 いーえるPの配信シングル。 KARENTレーベルの鏡音リンレン4周年 Append1周年記念企画で配信された作品の1つ。『交差する想像共感 SIDE-R』と同時リリース。 動画で発表した「POINT OF THE GLANCE」の別バージョンで、歌詞も一部異なっている。 曲目 POINT OF THE GLANCE - Another Ver （feat. 鏡音リン） リンク 作者サイト KARENT：「POINT OF THE GLANCE - Another Ver」 KARENT：「鏡音リン・レン祭'11」特集ページ コメント 名前 コメント
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Site and solution planning Infrastructure plannning 展開 WorkSheets DownLoadable WhitePaper Microsoft Office SharePoint Server 2007 Best Practices
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Format Title Artist Label Model Number Release Press 12 DANCEMAP2 EP TYT-K MOZAMBIQUE DISTRIBUTION,FIVE MINUTES RECORDS,ZAKI RECORDS TF-004 2000/--/-- - 034.jpg Side Track Title Produce A 1 I DON T WANNA LOSE YOUR LOVE feat.RAA DEE MITSUO "GEES" YANAGI 2 GET YOUR HANDS IN THE AIR feat.D.BINNSALINE,DEJUR TAKASHI FURUKAWA B 3 LAND OF A 1000 DANCES "INTENSIFY" feat.RAA DEE MITSUO "GEES" YANAGI 4 PRIVATE EYES feat.AGENT 99 TSUYOSHI "TAKA" TAKAYANAGI PERTAIN CD DANCE MAPII
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Maintenance and the device of institutions In order to get a user to get acquisition of knowledge, and the opportunity of learning, I have to have a media center visit first. If the institution is superannuated or it is user-unfriendly, though how much good media are substantial, nobody tries to visit. Then, the following two substantial points were planned as a device for getting as many users as possible to visit. Maintenance and the device of the exterior and interior equipment About the exterior, probably, it will be desirable to use the open exterior so that a user may drop in easily freely. Therefore, we decided to avoid the exterior [ exclusive ] with a cold image like concrete nakedness. The big glass window with the image which removes the fence of the inside which can overlook an inner situation, and outside was prepared, and also wood was used in plenty, and it was open and aimed at the warm exterior. About interior, you have to provide a user with two, the place which deepens "knowledge", and the place which offers peacefulness of the "heart", simultaneously. There was a bookshelf like the conventional library, the space of the straw mat which can be studied while relaxing not to mention arranging the desk which works for carrying out reading and study easily it being large was provided, and also the substantial single room space which can be learned in an individual or a group was planned. Moreover, it enabled it to utilize by preparing many Booth for the visual and auditory senses as a place which DVD is appreciated and also can feel at ease slowly in a single room. Barrier-free-izing of institutions If these institutions are people of not only a school but an area, they are the institutions which anyone can utilize widely. Therefore, the institution which is easy to use for people etc. which had an old person and an obstacle from the small child was aimed at, without limiting a user. In the conventional library, it seems that it is very hard to use for people with an old person or an obstacle. Then, in order to remove their handicap, I thought that barrier-free-izing the whole institution was also the first step which passes through an open institution. Specifically in consideration of the wheelchaired user and small children s thing, it tried not to make a bookshelf high. A push on the button installed the equipment which the bookshelf of the upper stage goes up and down automatically in the bookshelf which has become high inevitably. Moreover, the production of a simple and intelligible institution was aimed at so that it might be easy to use elderly people and handicapped persons. In addition to this, it is an institution which offers the environment which everyone tends to use supposing various things.
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■下記の設定の明確化と追加を行います。 １ 123p Heroes s Feastのサービス 下記のこの設定がないと、Heroes s Feastを出すためにお店にECL9以上でかつGreater Mark of HospitalityかDivine Caster 9レベル以上の者の存在または参加が不可欠（Heroes s FeastのScrollとかでも大分無理がありますし）となり、Eberron世界のパワー人口バランスに矛盾が発生するので追加します。 最低１１人以上、最大２０人までのLeast Mark of Hospitalityを持った各者が、同時にGreater DragonShard Focus ItemであるBag of Bounty 261pを所持し、Heroes s Feastの呪文を唱える行為の真似（勿論、本当に唱える事はできないが）をする事によって、１回だけ儀式参加人数分の食事量＝Caster LevelのHeroes s Feastの呪文の効果が発生させることが可能だとします。 １度この行為に参加したLeast Mark of Hospitalityを持った者は、８時間以上の完全休養を取らない限り、新たなにこの儀式に参加してHeroes s Feastを出すことはできません。つまり、１１人全員が完全に８時間以上完全休養した者達でなければならない、ということです。 また、Bag of Bounty 261pも１日に２回しかHeroes s Feastを出す儀式に使用できません。 料理代金はひとり分60gp、一式最低660gpから1200gpとします（すべて標準的価格）。 ■Using Action Points Augment a die roll One action point can be spent to add a bonus of +1d6 to one d20 roll. Activate a class ability If your character has a class ability usable a limited number of times per day, you can spend two action points to use the ability one additional time. For example, the human paladin can smite evil once per day, but you can spend two action points to do it a second time in the same day. Boost defense You can spend one action point as a free action to double the normal bonuses for fighting defensively. This gives a character a +4 dodge bonus to AC, +6 if it has 5 or more ranks in Tumble. Emulate feat You can spend one action point at the beginning of your round to gain the benefits of a feat for which your character meets the prerequisites but does not currently have. For example, the goblin fighter has a Dexterity of 15, so it meets the prerequisite for the Two-Weapon Fighting feat. You can spend an action point at the beginning of your round to reduce the penalties for the character to fight with two weapons at the same time. Extra attack You can spend one action point during a full attack action to gain an extra attack at your highest attack bonus. The attack can be either a melee or a ranged attack. For example, when the human monk takes a full attack action, it can either use flurry of blows for +1/+1 to hit, or make one attack with its longsword for +5 to hit. If you spend an action point the monk gains an additional attack, making its flurry of blows +1/+1/+1 to hit or +5/+5 with its longsword. Hasten infusion You can spend one action point to lower the casting time of one of the gnome artificer痴 infusions to 1 round. Spell boost You can spend one action point as a free action to increase your caster level for one spell you cast by 2. You must choose to spend the action point before you cast the spell. For example, you can spend an action point before the human wizard casts dispel magic from its scroll to boost its caster level to 4 instead of 3, improving the wizard痴 chances of successfully dispelling something. Spell recall You can spend one action point to retain a spell your character just cast (for those who prepare spells) or retain a spell slot for a spell your character just cast (for spontaneous casters). For example, you can spend an action point after your half-orc druid casts cure light wounds so it is still prepared and can be cast again, or you can spend an action point after your dwarf bard casts sleep from its repertoire to retain the spell slot. Stabilize You can spend one action point to automatically stabilize if dying. Improve feat You can spend an action point as a free action to improve a feat your character already has. Some examples are below. Blind-Fight You can eliminate your character痴 miss chance for a single attack. Combat Expertise You can double the bonus to AC granted by the feat, so taking a penalty of -1 on an attack roll gives your character a +2 dodge bonus to AC. Dodge You can increase the dodge bonus granted by the feat by +2, making it +3. Improved Critical You can double your critical range for one weapon (effectively tripling it, since it was doubled by the feat). This effect does not stack with any other effects that increase threat range (so it will not work in conjunction with the keen edge spell). Improved Initiative You can double the bonus for the feat, gaining a +8 bonus instead of +4. Metamagic feats You can spend an action point to apply a metamagic feat your character knows to a spell it is casting with no level increase and no casting time increase. 名前 コメント すべてのコメントを見る
https://w.atwiki.jp/pointofgrow/
Point Of Grow 公式HPへようこそ Point Of Grow（POfG）は大阪府で活動中のエンターテイメントバンドです。 今後は活動を広げさまざまな舞台で講演しますので、応援のほどよろしくお願いいたします
https://w.atwiki.jp/marvelheroes/pages/68.html
Prologue Avengers Tower Prologue Raft Landing Pad Cell Block Alpha S.H.I.E.L.D. Checkpoint Chapter 1 Avengers Tower S.H.I.E.L.D. Training Room S.H.I.E.L.D. Rooftop Checkpoint Abandoned Subway Blood Rose Entrance Chapter 2 Avengers Tower SHIPPING YARD (旧 Storage Yard) HIDDEN A.I.M. LABORATRY CRAB TRAP RESTAURANT (旧 Crab Shack) Taskmaster Institute CANNERY ROW CARGO BARGE (旧 Cargo Freighter) Chapter 3 Avengers Tower Buccaneer Beach Bamboo Forest Lowtown S.H.I.E.L.D. Recon Post Hand Tower Chapter 4 Avengers Tower Lower East Side Crosstown Subway Upper East side Fisk Tower Chapter 5 Xavier s School Wretched Slum Purifier Advance Base Ruined projects Morlock underground Old Trainyard Chapter 6 Xavier s School Hidden Camp Training Ground Outer Compound Command Bunker Chapter 7 Xavier s School Dinosaur Jungle Shield Science Station Mutant marsh Chapter 8 Shield Helicarrier AIM Weapon Facility Hydra Island Doomstatd outer Village Occupied Doomstadt
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Birdie and I went into separate rooms. Although Birdie had no visible wound, she should have been inspected. My blood on her face may have been mistaken for her own. A doctor and a nurse remained as I lay on a bed. The doctor frowned seeing my affected part. So, where is the piece? The doctor asked me like that. It was stupid of me to realize that at the last moment. I had left it with Birdie. Get it, please. The doctor s words made the nurse trot to the room for Birdie. I thought he was trying to divert my anxiety. What a simple soul I was. The doctor told the following story. The defendant had thrown to the roof of the next building the penis she had cut off. It is not certain that anyone being drunk can execute it, but she was drunk. She was 39 years old. The 28-year-old victim said he would marry her. He made her prostitute herself, and exerted frequent violence on her. She had not gone to prison for a year and a half after having appeared in court. Why do you think that was? The doctor said but the voice did not sound like a question. After a moment s pause he continued. The operation to join the penis to him took 11 hours. That surgery was a success, but much long time is required before all those functions would be recovered. The amount of penal infliction must depend upon the result of long-term treatment that is to clarify whether an erectile function is recovered or not, the court declared. She will merely wait, without being put in a prison for eighteen months until a medical report telling the result comes out. She is to be sentenced to more than eight years penal servitude if he could not have an erection of the penis. The nurse had not returned yet when the doctor finished. The doctor having lost his purpose went away to search the nurse at a brisk pace when I was left behind. Did I have a short dream? I broke the paper of food to throw the content toward the air. A pigeon flew down to eat it. The bird was lost to sight immediately. Throwing food repeatedly let me get tired of it finally. The pigeons like the picture on the pack of cigarettes called Peace were projected in my eyes. The pigeons in a row in many layers were extended in the sky. Hum! They look like kites, I muttered. There came a bee-like buzzing sound. The kites were spinning, driven by the wind. I felt dizzy. Lowering my eyes startled me, for I first saw a black object running on the wall. There was no way I could have insecticide, when the insect appeared suddenly. There was no newspaper that can be arms when rolled. A box of rubber bands just struck the eye. Recalling my childhood, I aimed at the insect with a rubber band I stretched out. PREV / NEXT The Point 1 / 2 / 3 / 4 / 5 / 6 / 7 / 8
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Gunpoint 機種：PC 作曲者：John Robert Matz、Ryan Ike、Francisco Cerda 開発元：Suspicious Developments 発売元：Suspicious Developments 発売年：2013 概要 Steamで配信されているインディーズゲーム。 ステルス要素のある2Dパズルアクションゲームで、主人公はスパイで施設に侵入して情報を盗み出すのが目的。 『エレベーターアクション』を思わせるレトロなグラフィックだが、シンプルな操作性と奥深い攻略性が人気を集めた。 残念ながら日本語未対応だが、アクションを楽しむ分には問題はないだろう。 BGMは全編ジャズ調の楽曲が使われていて、どの曲もインディーズとは思えないほど本格的。 常に夜陰に紛れて行動するスパイらしい渋さが表現されている。ステージBGMはCrosslinkモードに入るとアレンジが変化する。 収録曲(サウンドトラック順) 曲名 作・編曲者 補足 順位 Main Theme (Melancholia) John Robert Matz Opening Security, Circuitry and You Ryan Ike Rooke Caught on Camera Mission Round Gunpoint Francisco Cerda Main Menu Subterfuge Shuffle Ryan Ike Rooke Crossed Wires Subterfuge Shuffle - Crosslink R.I.P.I. Unused Cold Halls and Footfalls Rooke Mains Cold Halls and Footfalls - Crosslink Run for It! John Robert Matz Unused The Five-Floor Goodbye Ryan Ike Rooke The Prototype The Five-Floor Goodbye - Crosslink End of the Line John Robert Matz Dig Ryan Ike Rooke The Trace Dig - Crosslink High-Tail It! Unused Leviathan Rooke The Killer Leviathan - Crosslink One-Stop Spy Shop Unused Defenestraight To My Heart Stealth Crawls and Dance Halls (Cover/Mashup) John Robert Matz Melancholia Waltz (Cover) Francisco Cerda Electric Fedora John Robert Matz Gunpoint Rewired (Remix) Ryan Ike Fin John Robert Matz サウンドトラック Gunpoint - The Soundtrack PV
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Hematopoietic cell regulation by Rac1 and Rac2 BTK-/- mice show impaired responsiveness to Epo. BTK-/-/TEC-/- plateles fail to undergo an inccrease in Ca2+ , aggregation, secretion, and spreading in response to collagen or CRP. PLCG2 -/- mice impair vasculogenesis and erythropoiesis. Jak2 -/- mice show defective erythropoiesis. RasGRP2 -/- mice have a platelet aggregation defect. Hematopoietic cell regulation by Rac1 and Rac2 1 Science. 2003 Oct 17;302(5644) 445-9. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA. Division of Experimental Hematology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA. The Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 are critical signaling regulators in mammalian cells. The deletion of both Rac1 and Rac2 murine alleles leads to a massive egress of hematopoietic stem/progenitor cells (HSC/Ps) into the blood from the marrow, whereas Rac1-/- but not Rac2-/- HSC/Ps fail to engraft in the bone marrow of irradiated recipient mice. In contrast, Rac2, but not Rac1, regulates superoxide production and directed migration in neutrophils, and in each cell type, the two GTPases play distinct roles in actin organization, cell survival, and proliferation. Thus, Rac1 and Rac2 regulate unique aspects of hematopoietic development and function. Publication Types Research Support, U.S. Gov t, P.H.S. PMID 14564009 [PubMed - indexed for MEDLINE] BTK-/- mice show impaired responsiveness to Epo. 1 J Exp Med. 2004 Mar 15;199(6) 785-95. Epub 2004 Mar 8. Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. Schmidt U, van den Akker E, Parren-van Amelsvoort M, Litos G, de Bruijn M, Gutierrez L, Hendriks RW, Ellmeier W, Lowenberg B, Beug H, von Lindern M. Institute of Molecular Pathology, Vienna, Austria. Regulation of survival, expansion, and differentiation of erythroid progenitors requires the well-controlled activity of signaling pathways induced by erythropoietin (Epo) and stem cell factor (SCF). In addition to qualitative regulation of signaling pathways, quantitative control may be essential to control appropriate cell numbers in peripheral blood. We demonstrate that Bruton s tyrosine kinase (Btk) is able to associate with the Epo receptor (EpoR) and Jak2, and is a substrate of Jak2. Deficiency of Btk results in reduced and delayed phosphorylation of the EpoR, Jak2, and downstream signaling molecules such as Stat5 and PLCgamma1 as well as in decreased responsiveness to Epo. As a result, expansion of erythroid progenitors lacking Btk is impaired at limiting concentrations of Epo and SCF. In addition, we show that SCF induces Btk to interact with TNF-related apoptosis-inducing ligand (TRAIL)-receptor 1 and that lack of Btk results in increased sensitivity to TRAIL-induced apoptosis. Together, our results indicate that Btk is a novel, quantitative regulator of Epo/SCF-dependent expansion and survival in erythropoiesis. Publication Types Comparative Study Research Support, Non-U.S. Gov t PMID 15007095 [PubMed - indexed for MEDLINE] BTK-/-/TEC-/- plateles fail to undergo an inccrease in Ca2+ , aggregation, secretion, and spreading in response to collagen or CRP. 1 Blood. 2003 Nov 15;102(10) 3592-9. Epub 2003 Jul 3. Tec regulates platelet activation by GPVI in the absence of Btk. Atkinson BT, Ellmeier W, Watson SP. Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, United Kingdom. ben.atkinson@pharm.ox.ac.uk The Tec family kinase Btk plays an important role in the regulation of phospholipase C gamma 2 (PLC gamma 2) downstream of the collagen receptor glycoprotein VI (GPVI) in human platelets. Platelets also express a second member of this family, Tec; however, its function has not been analyzed. To address the role of Tec, we analyzed Btk-/-, Tec-/-, and Btk/Tec double-deficient (Btk-/-/Tec-/-) platelets. Tec-/- platelets exhibit a minor reduction in aggregation to threshold concentrations of collagen or the GPVI-specific agonist collagen-related peptide (CRP), whereas responses to higher concentrations are normal. Tyrosine phosphorylation of PLC gamma 2 by collagen and CRP is not altered in Tec-/- platelets. However, Btk-/-/Tec-/- platelets exhibit a greater reduction in PLC gamma 2 phosphorylation than is seen in the absence of Btk, thus revealing an important role for Tec in this situation. Furthermore, Btk-/-/Tec-/- platelets fail to undergo an increase in Ca2+, aggregation, secretion, and spreading in response to collagen or CRP, whereas they aggregate normally to adenosine diphosphate (ADP) and spread on fibrinogen. A residual GPVI signal exists in the Btk-/-/Tec-/- platelets as CRP synergizes with ADP to mediate aggregation. These results demonstrate an essential requirement for Tec and Btk in platelet activation by GPVI and reveal a functional role for Tec in the regulation of PLC gamma 2 in the absence of Btk. Publication Types Research Support, Non-U.S. Gov t PMID 12842985 [PubMed - indexed for MEDLINE] PLCG2 -/- mice impair vasculogenesis and erythropoiesis. 1 J Biol Chem. 2002 Mar 15;277(11) 9335-41. Epub 2001 Dec 13. Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. Liao HJ, Kume T, McKay C, Xu MJ, Ihle JN, Carpenter G. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232,USA. Mice nullizygous for Plcg1 cease growing at early to mid-gestation. An examination of carefully preserved wild-type embryos shows clear evidence of erythropoiesis, but erythropoiesis is not evident in Plcg1 nullizygous embryos at the same stage. The analyses of embryonic materials demonstrate that in the absence of Plcg1, erythroid progenitors cannot be detected in the yolk sac or embryo body by three different assays, burst-forming units, colony-forming units, and analysis for the developmental marker Ter119. However, non-erythroid granulocyte/macrophage colonies are produced by Plcg1 null embryos. Further analysis of these embryos demonstrates significantly diminished vasculogenesis in Plcg1 nullizygous embryos based on the lack of expression of the endothelial marker platelet endothelial cell adhesion molecule-1. In addition, Plcg1 nullizygous embryos express a greatly reduced level of vascular endothelial growth factor receptor-2/Flk-1, consistent with significantly impaired vasculogenesis and erythropoiesis. Interestingly, these early embryos do express phospholipase C-gamma2, however, it is unable to substitute for the absence of phospholipase C-gamma1, which can be detected in its tyrosine-phosphorylated state. Publication Types Research Support, U.S. Gov t, P.H.S. PMID 11744703 [PubMed - indexed for MEDLINE] Jak2 -/- mice show defective erythropoiesis. 1 Cell. 1998 May 1;93(3) 397-409. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K. Institute of Medical Microbiology, Immunology, and Hygiene, Technical University of Munich, Germany. Janus kinases (Jaks) play an important role in signal transduction via cytokine and growth factor receptors. A targeted inactivation of Jak2 was performed. Jak2-/- embryos are anemic and die around day 12.5 postcoitum. Primitive erythrocytes are found, but definitive erythropoiesis is absent. Compared to erythropoietin receptor-deficient mice, the phenotype of Jak2 deficiency is more severe. Fetal liver BFU-E and CFU-E colonies are completely absent. However, multilineage hematopoietic stem cells (CD34low, c-kit(pos)) can be found, and B lymphopoiesis appears intact. In contrast to IFNalpha stimulation, Jak2-/- cells do not respond to IFNgamma. Jak2-/- embryonic stem cells are competent for LIF signaling. The data provided demonstrate that Jak2 has pivotal functions for signal transduction of a set of cytokine receptors required in definitive erythropoiesis. Publication Types PMID 9590174 [PubMed - indexed for MEDLINE] RasGRP2 -/- mice have a platelet aggregation defect. 1 Nat Med. 2004 Sep;10(9) 982-6. Epub 2004 Aug 29. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Crittenden JR, Bergmeier W, Zhang Y, Piffath CL, Liang Y, Wagner DD, Housman DE, Graybiel AM. Department of Brain and Cognitive Sciences, and McGovern Institute for Brain Research, Massachusetts Institute of Technology, 45 Carleton Street, E25-618, Cambridge, Massachusetts 02139, USA. Signaling through the second messengers calcium and diacylglycerol (DAG) is a critical element in many biological systems. Integration of calcium and DAG signals has been suggested to occur primarily through protein kinase C family members, which bind both calcium and DAG. However, an alternative pathway may involve members of the CalDAG-GEF/RasGRP protein family, which have structural features (calcium-binding EF hands and DAG-binding C1 domains) that suggest they can function in calcium and DAG signal integration. To gain insight into the signaling systems that may be regulated by CalDAG-GEF/RasGRP family members, we have focused on CalDAG-GEFI, which is expressed preferentially in the brain and blood. Through genetic ablation in the mouse, we have found that CalDAG-GEFI is crucial for signal integration in platelets. Mouse platelets that lack CalDAG-GEFI are severely compromised in integrin-dependent aggregation as a consequence of their inability to signal through CalDAG-GEFI to its target, the small GTPase Rap1. These results suggest that analogous signaling defects are likely to occur in the central nervous system when CalDAG-GEFI is absent or compromised in function. Publication Types PMID 15334074 [PubMed - indexed for MEDLINE]